Employing a PLGA-TPGS based nanoparticle to improve the ocular delivery of Acyclovir

Employing a PLGA-TPGS based nanoparticle to improve the ocular delivery of Acyclovir

Delivering drugs via the ocular route has always been a challenge for poorly soluble drugs. The various anatomical and physiological barriers in the eye cavity hinder the residence of drugs within the corneal and precorneal regions. In this study, the nanosystem that could sufficiently deliver the p...

Full description

Bibliographic Details
Main Authors:	Musaed Alkholief, Hammam Albasit, Adel Alhowyan, Sultan Alshehri, Mohammad Raish, Mohd Abul Kalam, Aws Alshamsan
Format:	Article
Language:	English
Published:	Elsevier 2019-02-01
Series:	Saudi Pharmaceutical Journal
Online Access:	http://www.sciencedirect.com/science/article/pii/S1319016418305796

Similar Items

The Design of Anionic Surfactant-Based Amino-Functionalized Mesoporous Silica Nanoparticles and their Application in Transdermal Drug Delivery
by: Aliyah Almomen, et al.
Published: (2020-10-01)

Thermoresponsive sol-gel improves ocular bioavailability of Dipivefrin hydrochloride and potentially reduces the elevated intraocular pressure in vivo
by: Musaed Alkholief, et al.
Published: (2020-08-01)

Development and Evaluation of Chitosan Nanoparticles for Ocular Delivery of Tedizolid Phosphate
by: Alkholief, M., et al.
Published: (2022)

Development and Evaluation of Chitosan Nanoparticles for Ocular Delivery of Tedizolid Phosphate
by: Alkholief, M., et al.
Published: (2022)

Oral Delivery of DMAB-Modified Docetaxel-Loaded PLGA-TPGS Nanoparticles for Cancer Chemotherapy
by: Zeng Xiaowei, et al.
Published: (2011-01-01)

GE11 Modified PLGA/TPGS Nanoparticles Targeting Delivery of Salinomycin to Breast Cancer Cells
by: Kaichun Li MD, et al.
Published: (2021-05-01)

Co-Delivery of Docetaxel and Salinomycin to Target Both Breast Cancer Cells and Stem Cells by PLGA/TPGS Nanoparticles
by: Gao J, et al.
Published: (2019-11-01)

PLGA implants for ocular drug delivery
by: Bode, Corinna
Published: (2019)

Formulation, Characterization And Evaluation Of Curcumin- Loaded PLGA- TPGS Nanoparticles For Liver Cancer Treatment
by: Chen XP, et al.
Published: (2019-10-01)

Robust aptamer–polydopamine-functionalized M-PLGA–TPGS nanoparticles for targeted delivery of docetaxel and enhanced cervical cancer therapy
by: Xu GJ, et al.
Published: (2016-06-01)

LCR based quick detection of hotspot G1896A mutation in patients with different spectrum of hepatitis B
by: Abdul Malik, et al.
Published: (2021-05-01)

Garcinol loaded vitamin E TPGS emulsified PLGA nanoparticles: preparation, physicochemical characterization, in vitro and in vivo studies
by: Raghuvir H. Gaonkar, et al.
Published: (2017-04-01)

Buccal mucoadhesive delivery system of acyclovir
by: Shojaei, Amir Hossein
Published: (1997)

Effect of cryoprotection on particle size stability and preservation of chitosan nanoparticles with and without hyaluronate or alginate coating
by: Abdulaziz Almalik, et al.
Published: (2017-09-01)

Taxifolin, a natural flavonoid interacts with cell cycle regulators causes cell cycle arrest and causes tumor regression by activating Wnt/ β -catenin signaling pathway
by: Suhail Razak, et al.
Published: (2018-10-01)

Pseudoboehmite as a drug delivery system for acyclovir
by: Renato Meneghetti Peres, et al.
Published: (2021-07-01)

The use of chitosan-coated flexible liposomes as a remarkable carrier to enhance the antitumor efficacy of 5-fluorouracil against colorectal cancer
by: Abdullah Alomrani, et al.
Published: (2019-07-01)

Acyclovir Suppression to Prevent Recurrent Genital Herpes at Delivery
by: L. L. Scott, et al.
Published: (2002-01-01)

Liquid crystalline systems containing Vitamin E TPGS for the controlled transdermal nicotine delivery
by: Lívia Neves Borgheti-Cardoso, et al.

Formulation and optimization of mucoadhesive nano drug delivery system of acyclovir
by: Uday Bhosale, et al.
Published: (2012-01-01)

Topical delivery of different ketoconazole and acyclovir formulations / Danélia Botes
by: Botes, Danélia
Published: (2013)

Topical delivery of different ketoconazole and acyclovir formulations / Danélia Botes
by: Botes, Danélia
Published: (2013)

Deleterious effect of angiotensin-converting enzyme gene polymorphism in vitiligo patients
by: Nosiba Suliman Basher, et al.
Published: (2021-08-01)

Design and Development of D‒α‒Tocopheryl Polyethylene Glycol Succinate‒<i>block</i>‒Poly(ε-Caprolactone) (TPGS−<i>b</i>−PCL) Nanocarriers for Solubilization and Controlled Release of Paclitaxel
by: Osman Yusuf, et al.
Published: (2021-05-01)

Superiority of TPGS-loaded micelles in the brain delivery of vinpocetine via administration of thermosensitive intranasal gel
by: Ahmed TA, et al.
Published: (2019-07-01)

Poloxamer 407/TPGS mixed micelles for delivery of gambogic acid to breast and multidrug-resistant cancer
by: Hussain MD, et al.
Published: (2012-02-01)

Paradoxical Signaling Pathways in Developing Thymocytes
by: Aws Alshamsan
Published: (2011-10-01)

STAT3-siRNA induced B16.F10 melanoma cell death: more association with VEGF downregulation than p-STAT3 knockdown
by: Aws Alshamsan
Published: (2018-12-01)

Development of stat-3 targeting siRNA nano-carriers for cancer therapy
by: Alshamsan, Aws
Published: (2010)

Systems Biology Approaches for the Prediction of Possible Role of Chlamydia pneumoniae Proteins in the Etiology of Lung Cancer.
by: Shahanavaj Khan, et al.
Published: (2016-01-01)

Vitamin E TPGS based transferosomes augmented TAT as a promising delivery system for improved transdermal delivery of raloxifene.
by: Nabil A Alhakamy, et al.
Published: (2019-01-01)

The effect of Brij 97 and carrageenan on the transdermal delivery of acyclovir / Maderi Roestorf
by: Roestorf, Maderi
Published: (2009)

The effect of Brij 97 and carrageenan on the transdermal delivery of acyclovir / Maderi Roestorf
by: Roestorf, Maderi
Published: (2009)

Development and evaluation of acyclovir microemulsion as oral and topical drug delivery systems
by: Ling-FangHsu, et al.
Published: (2014)

Stability and ocular biodistribution of topically administered PLGA nanoparticles
by: Sean Swetledge, et al.
Published: (2021-06-01)

Solubility improvement and percutaneous penetration enhancement of estradiol by TPGS
by: Shin-Yi, et al.
Published: (2001)

Synthesis, Characterization and Safety Evaluation of Sericin-Based Hydrogels for Controlled Delivery of Acyclovir
by: Moawia M. Al-Tabakha, et al.
Published: (2021-03-01)

Investigating the Potential of Transdermal Delivery of Avanafil Using Vitamin E-TPGS Based Mixed Micelles Loaded Films
by: Abdullah A. Alamoudi, et al.
Published: (2021-05-01)

Development and Characterization of PLGA Nanoparticle-Laden Hydrogels for Sustained Ocular Delivery of Norfloxacin in the Treatment of Pseudomonas Keratitis: An Experimental Study
by: Gebreel RM, et al.
Published: (2021-02-01)

Dual Drug Delivery of Sorafenib and Doxorubicin from PLGA and PEG-PLGA Polymeric Nanoparticles
by: György Babos, et al.
Published: (2018-08-01)

Cannot write session to /tmp/vufind_sessions/sess_rurdjtas18t15rv6euvr3120a2