SOX30 Inhibits Tumor Metastasis through Attenuating Wnt-Signaling via Transcriptional and Posttranslational Regulation of β-Catenin in Lung Cancer

SOX30 Inhibits Tumor Metastasis through Attenuating Wnt-Signaling via Transcriptional and Posttranslational Regulation of β-Catenin in Lung Cancer

Although high mortality of lung cancer is greatly due to distant metastasis, the mechanism of this metastasis remains unclear. Here, we investigate in lung cancer that SOX30 is sharply under-expressed in metastatic tumors compared with non-metastatic tumors, and suppresses plenty of metastasis relat...

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Bibliographic Details
Main Authors: Fei Han, Wen-bin Liu, Xiao-yan Shi, Jun-tang Yang, Xi Zhang, Zhi-ming Li, Xiao Jiang, Li Yin, Jian-jun Li, Chuan-shu Huang, Jia Cao, Jin-yi Liu
Format: Article
Language:English
Published: Elsevier 2018-05-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396418301543

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http://www.sciencedirect.com/science/article/pii/S2352396418301543

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