The prevalence of depression among adolescent with HIV/AIDS: a systematic review and meta-analysis
Abstract Background Depression is particularly common among adolescents with HIV/AIDS and has been associated with disruption of the important developmental process, subsequently leading to a wide range of negative mental, physical and psychosocial consequences, as well as poor quality of life in th...
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doaj-8418e567982f4858af390b4838cb32782021-05-02T11:28:44ZengBMCAIDS Research and Therapy1742-64052021-04-0118111010.1186/s12981-021-00351-1The prevalence of depression among adolescent with HIV/AIDS: a systematic review and meta-analysisGetinet Ayano0Sileshi Demelash1Mebratu Abraha2Light Tsegay3Research and Training Department, Amanuel Mental Specialized HospitalDepartment of Psychiatry, Paulo’s Millennium Medical CollegeEthiopian Public Health InstituteDepartmemt of Psychiatry, Aksum UniversityAbstract Background Depression is particularly common among adolescents with HIV/AIDS and has been associated with disruption of the important developmental process, subsequently leading to a wide range of negative mental, physical and psychosocial consequences, as well as poor quality of life in those population groups. Nevertheless, to the best of our knowledge, there are no prior systematic reviews and meta-analytic studies that determined the prevalence of depression among adolescents with HIV/AIDS. Method We systematically searched PubMed, Scopus and Web of Science for relevant literature until May 2020. A random-effect meta-analysis was used to pool prevalence rates from individual studies. Sensitivity and subgroup analyses were performed to identify the source of heterogeneities and to compare the prevalence estimates across the groups. The Joanna Briggs Institute’s quality assessment checklist was used to evaluate the quality of the included studies. Cochran’s Q and the I2 tests were used to assess heterogeneity between the studies. Results A total of ten studies were included for the final analysis, with 2642 adolescents living with HIV/AIDS. Our final meta-analysis showed that more than a quarter of adolescents with HIV had depression [26.07% (95% CI 18.92–34.78)]. The prevalence was highest amongst female adolescents (32.15%) than males (25.07%) as well as amongst the older adolescents aged 15–19 years (37.09%) than younger adolescents aged 10–14 years (29.82%). Conclusion Our study shows that a significant proportion of adolescents with HIV had depression, indicating the imperativeness of intervention strategies to alleviate the suffering and possibly reduce the probable negative ramifications.https://doi.org/10.1186/s12981-021-00351-1DepressionAdolescentHIVAIDSSystematic reviewMeta-analysis |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Getinet Ayano Sileshi Demelash Mebratu Abraha Light Tsegay |
spellingShingle |
Getinet Ayano Sileshi Demelash Mebratu Abraha Light Tsegay The prevalence of depression among adolescent with HIV/AIDS: a systematic review and meta-analysis AIDS Research and Therapy Depression Adolescent HIV AIDS Systematic review Meta-analysis |
author_facet |
Getinet Ayano Sileshi Demelash Mebratu Abraha Light Tsegay |
author_sort |
Getinet Ayano |
title |
The prevalence of depression among adolescent with HIV/AIDS: a systematic review and meta-analysis |
title_short |
The prevalence of depression among adolescent with HIV/AIDS: a systematic review and meta-analysis |
title_full |
The prevalence of depression among adolescent with HIV/AIDS: a systematic review and meta-analysis |
title_fullStr |
The prevalence of depression among adolescent with HIV/AIDS: a systematic review and meta-analysis |
title_full_unstemmed |
The prevalence of depression among adolescent with HIV/AIDS: a systematic review and meta-analysis |
title_sort |
prevalence of depression among adolescent with hiv/aids: a systematic review and meta-analysis |
publisher |
BMC |
series |
AIDS Research and Therapy |
issn |
1742-6405 |
publishDate |
2021-04-01 |
description |
Abstract Background Depression is particularly common among adolescents with HIV/AIDS and has been associated with disruption of the important developmental process, subsequently leading to a wide range of negative mental, physical and psychosocial consequences, as well as poor quality of life in those population groups. Nevertheless, to the best of our knowledge, there are no prior systematic reviews and meta-analytic studies that determined the prevalence of depression among adolescents with HIV/AIDS. Method We systematically searched PubMed, Scopus and Web of Science for relevant literature until May 2020. A random-effect meta-analysis was used to pool prevalence rates from individual studies. Sensitivity and subgroup analyses were performed to identify the source of heterogeneities and to compare the prevalence estimates across the groups. The Joanna Briggs Institute’s quality assessment checklist was used to evaluate the quality of the included studies. Cochran’s Q and the I2 tests were used to assess heterogeneity between the studies. Results A total of ten studies were included for the final analysis, with 2642 adolescents living with HIV/AIDS. Our final meta-analysis showed that more than a quarter of adolescents with HIV had depression [26.07% (95% CI 18.92–34.78)]. The prevalence was highest amongst female adolescents (32.15%) than males (25.07%) as well as amongst the older adolescents aged 15–19 years (37.09%) than younger adolescents aged 10–14 years (29.82%). Conclusion Our study shows that a significant proportion of adolescents with HIV had depression, indicating the imperativeness of intervention strategies to alleviate the suffering and possibly reduce the probable negative ramifications. |
topic |
Depression Adolescent HIV AIDS Systematic review Meta-analysis |
url |
https://doi.org/10.1186/s12981-021-00351-1 |
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