Safety Assessment of Compounds after In Vitro Metabolic Conversion Using Zebrafish Eleuthero Embryos

Safety Assessment of Compounds after In Vitro Metabolic Conversion Using Zebrafish Eleuthero Embryos

Zebrafish-based platforms have recently emerged as a useful tool for toxicity testing as they combine the advantages of in vitro and in vivo methodologies. Nevertheless, the capacity to metabolically convert xenobiotics by zebrafish eleuthero embryos is supposedly low. To circumvent this concern, a...

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Bibliographic Details
Main Authors: Arianna Giusti, Xuan-Bac Nguyen, Stanislav Kislyuk, Mélanie Mignot, Cecilia Ranieri, Johan Nicolaï, Marlies Oorts, Xiao Wu, Pieter Annaert, Noémie De Croze, Marc Léonard, Annelii Ny, Deirdre Cabooter, Peter de Witte
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:International Journal of Molecular Sciences
Subjects:
drug discovery
toxicity
microsomes
metabolism
zebrafish eleuthero embryos
Online Access:https://www.mdpi.com/1422-0067/20/7/1712

Internet

https://www.mdpi.com/1422-0067/20/7/1712

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