Cytoprotective effects of olesoxime on isolated human pancreatic islets in order to attenuate apoptotic pathway

Cytoprotective effects of olesoxime on isolated human pancreatic islets in order to attenuate apoptotic pathway

Background and purpose: Islet transplantation is considered as a promising approach in the treatment of diabetes type 1. In this regard, optimal culture of the pancreatic islets is promising in the success of transplantation. In the present study, the effect of olesoxime, as an antiapoptotic substan...

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Bibliographic Details
Main Authors: Maryam Kaviani, Somayeh Keshtkar, Negar Azarpira, Mahdokht Hossein Aghdaei, Bita Geramizadeh, Mohammad Hossein Karimi, Alireza Shamsaeefar, Nasrin Motazedian, Saman Nikeghbalian, Ismail H. Al-Abdullah, Mohammad Hossein Ghahremani
Format: Article
Language:English
Published: Elsevier 2019-04-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Human pancreatic islet
Culture
Olesoxime
Viability
Functionality
Apoptosis
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332218384750

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http://www.sciencedirect.com/science/article/pii/S0753332218384750

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