Palmitoylethanolamide Supplementation during Sensitization Prevents Airway Allergic Symptoms in the Mouse

Palmitoylethanolamide Supplementation during Sensitization Prevents Airway Allergic Symptoms in the Mouse

One important risk factor for the development of asthma is allergen sensitization. Recent increasing evidence suggests a prominent role of mast cells in asthma pathophysiology. Since Palmitoylethanolamide (PEA), an endogenous lipid mediator chemically related to – and co-released with- the endocanna...

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Bibliographic Details
Main Authors: Fiorentina Roviezzo, Antonietta Rossi, Elisabetta Caiazzo, Pierangelo Orlando, Maria A. Riemma, Valentina M. Iacono, Andrea Guarino, Armando Ialenti, Carla Cicala, Alessio Peritore, Raffaele Capasso, Vincenzo Di Marzo, Angelo A. Izzo
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-12-01
Series:Frontiers in Pharmacology
Subjects:
palmitoylethanolamide
mast cells
allergen sensitization
bronchial hyperreactivity
airway inflammation
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2017.00857/full

Internet

http://journal.frontiersin.org/article/10.3389/fphar.2017.00857/full

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