Noninvasive Detection of Extracellular pH in Human Benign and Malignant Liver Tumors Using CEST MRI

Noninvasive Detection of Extracellular pH in Human Benign and Malignant Liver Tumors Using CEST MRI

PurposeIn this study, we aimed to use 3T magnetic resonance imaging (MRI), which is clinically available, to determine the extracellular pH (pHe) of liver tumors and prospectively evaluate the ability of chemical exchange saturation transfer (CEST) MRI to distinguish between benign and malignant liv...

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Main Authors: Yanyan Tang, Gang Xiao, Zhiwei Shen, Caiyu Zhuang, Yudan Xie, Xiaolei Zhang, Zhongxian Yang, Jitian Guan, Yuanyu Shen, Yanzi Chen, Lihua Lai, Yuanfeng Chen, Shuo Chen, Zhuozhi Dai, Runrun Wang, Renhua Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Oncology
Subjects:
extracellular pH
ioversol
chemical exchange saturation transfer magnetic resonance imaging (MRI)
hepatic carcinoma
hepatic hemangioma
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.578985/full

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https://www.frontiersin.org/articles/10.3389/fonc.2020.578985/full

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