Increased prevalence of pfdhfr and pfdhps mutations associated with sulfadoxine–pyrimethamine resistance in Plasmodium falciparum isolates from Jazan Region, Southwestern Saudi Arabia: important implications for malaria treatment policy

Increased prevalence of pfdhfr and pfdhps mutations associated with sulfadoxine–pyrimethamine resistance in Plasmodium falciparum isolates from Jazan Region, Southwestern Saudi Arabia: important implications for malaria treatment policy

Abstract Background Despite significant progress in eliminating malaria from the Kingdom of Saudi Arabia, the disease is still endemic in the southwestern region of the country. Artesunate plus sulfadoxine–pyrimethamine (AS + SP) has been used in Saudi Arabia since 2007 as a first-line treatment for...

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Bibliographic Details
Main Authors: Aymen M. Madkhali, Hesham M. Al-Mekhlafi, Wahib M. Atroosh, Ahmad Hassn Ghzwani, Khalid Ammash Zain, Ahmed A. Abdulhaq, Khalid Y. Ghailan, Alkhansa A. Anwar, Zaki M. Eisa
Format: Article
Language:English
Published: BMC 2020-12-01
Series:Malaria Journal
Subjects:
Malaria
Plasmodium falciparum
Artemisinin-based combination therapy
Drug resistance
Infectious diseases
Saudi Arabia
Online Access:https://doi.org/10.1186/s12936-020-03524-x

Internet

https://doi.org/10.1186/s12936-020-03524-x

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