Increased prevalence of pfdhfr and pfdhps mutations associated with sulfadoxine–pyrimethamine resistance in Plasmodium falciparum isolates from Jazan Region, Southwestern Saudi Arabia: important implications for malaria treatment policy
Abstract Background Despite significant progress in eliminating malaria from the Kingdom of Saudi Arabia, the disease is still endemic in the southwestern region of the country. Artesunate plus sulfadoxine–pyrimethamine (AS + SP) has been used in Saudi Arabia since 2007 as a first-line treatment for...
Main Authors: | Aymen M. Madkhali, Hesham M. Al-Mekhlafi, Wahib M. Atroosh, Ahmad Hassn Ghzwani, Khalid Ammash Zain, Ahmed A. Abdulhaq, Khalid Y. Ghailan, Alkhansa A. Anwar, Zaki M. Eisa |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-12-01
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Series: | Malaria Journal |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12936-020-03524-x |
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