A Two-Headed Monster to Avert Disaster: HBS1/SKI7 Is Alternatively Spliced to Build Eukaryotic RNA Surveillance Complexes

A Two-Headed Monster to Avert Disaster: HBS1/SKI7 Is Alternatively Spliced to Build Eukaryotic RNA Surveillance Complexes

The cytosolic RNA exosome, a 3′→5′ exoribonuclease complex, contributes to mRNA degradation in eukaryotes, limiting the accumulation of poorly-translated, improperly translated, or aberrant mRNA species. Disruption of cytosolic RNA exosome activity allows aberrant RNA species to accumulate, which ca...

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Bibliographic Details
Main Authors: Jacob O. Brunkard, Barbara Baker
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Plant Science
Subjects:
RNA exosome
innate immunity
antiviral defense
RNA interference
alternative splicing
HBS1
Online Access:https://www.frontiersin.org/article/10.3389/fpls.2018.01333/full

Internet

https://www.frontiersin.org/article/10.3389/fpls.2018.01333/full

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