Downregulation of antigen presentation-associated pathway proteins is linked to poor outcome in triple-negative breast cancer patient tumors

Downregulation of antigen presentation-associated pathway proteins is linked to poor outcome in triple-negative breast cancer patient tumors

Triple-negative breast cancer (TNBC) is a heterogeneous subtype with varying disease outcomes. Tumor-infiltrating lymphocytes (TILs) are frequent in TNBC and have been shown to correlate with outcome, suggesting an immunogenic component in this subtype. However, other factors intrinsic to the cancer...

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Bibliographic Details
Main Authors: Martin H. Pedersen, Brian L. Hood, Hans Christian Beck, Thomas P. Conrads, Henrik J. Ditzel, Rikke Leth-Larsen
Format: Article
Language:English
Published: Taylor & Francis Group 2017-05-01
Series:OncoImmunology
Subjects:
basal-like breast cancer
biomarker
formalin-fixed paraffin embedded
major histocompatibility complex
mass spectrometry
mhc class i antigen presentation pathway
proteomics
triple-negative breast cancer
Online Access:http://dx.doi.org/10.1080/2162402X.2017.1305531

Internet

http://dx.doi.org/10.1080/2162402X.2017.1305531

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