Isolation of F. novicida-Containing Phagosome from Infected Human Monocyte Derived Macrophages

Isolation of F. novicida-Containing Phagosome from Infected Human Monocyte Derived Macrophages

Francisella is a gram-negative bacterial pathogen, which causes tularemia in humans and animals. A crucial step of Francisella infection is its invasion of macrophage cells. Biogenesis of the Francisella-containing phagosome (FCP) is arrested for ~15 min at the endosomal stage, followed by gradual b...

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Bibliographic Details
Main Authors: Valentina Marecic, Olga Shevchuk, Mateja Ozanic, Mirna Mihelcic, Michael Steinert, Antonija Jurak Begonja, Yousef Abu Kwaik, Marina Santic
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-07-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
phagocytosis
organelle purification
pathogen-containing phagosomes
Francisella
human macrophages
Online Access:http://journal.frontiersin.org/article/10.3389/fcimb.2017.00303/full

Internet

http://journal.frontiersin.org/article/10.3389/fcimb.2017.00303/full

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