Acute SIV infection in sooty mangabey monkeys is characterized by rapid virus clearance from lymph nodes and absence of productive infection in germinal centers.

Acute SIV infection in sooty mangabey monkeys is characterized by rapid virus clearance from lymph nodes and absence of productive infection in germinal centers.

Lymphoid tissue immunopathology is a characteristic feature of chronic HIV/SIV infection in AIDS-susceptible species, but is absent in SIV-infected natural hosts. To investigate factors contributing to this difference, we compared germinal center development and SIV RNA distribution in peripheral ly...

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Bibliographic Details
Main Authors: Amanda J Martinot, Mareike Meythaler, Lu-Ann Pozzi, Karen Dalecki Boisvert, Heather Knight, Dennis Walsh, Susan Westmoreland, Daniel C Anderson, Amitinder Kaur, Shawn P O'Neil
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3589484?pdf=render

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http://europepmc.org/articles/PMC3589484?pdf=render

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