Spiculisporic Acids B–D, Three New γ-Butenolide Derivatives from a Sea Urchin-Derived Fungus Aspergillus sp. HDf2
Three new γ-butenolide derivatives 1–3, named spiculisporic acids B–D, were isolated from the culture of Aspergillus sp. HDf2, a marine-derived fungus that resides in the sea urchin, Anthocidaris crassispina. The structures of 1–3 were elucidate...
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| Format: | Article |
| Language: | English |
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MDPI AG
2012-11-01
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| Series: | Molecules |
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| Online Access: | http://www.mdpi.com/1420-3049/17/11/13175 |
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doaj-85fc05144d1544bc9bfce7863717fea02020-11-24T21:03:10ZengMDPI AGMolecules1420-30492012-11-011711131751318210.3390/molecules171113175Spiculisporic Acids B–D, Three New γ-Butenolide Derivatives from a Sea Urchin-Derived Fungus Aspergillus sp. HDf2Xian-Ming TangQuan-Ying FengMing-Qiu YangMing-Hui ShenTian-Mi LiuRong WangXiang-Min LiThree new γ-butenolide derivatives 1–3, named spiculisporic acids B–D, were isolated from the culture of Aspergillus sp. HDf2, a marine-derived fungus that resides in the sea urchin, Anthocidaris crassispina. The structures of 1–3 were elucidated on the basis of spectroscopic methods, including MS and 2D NMR techniques. Their in vitro cytotoxic activities against two cell lines (SGC-7901, human gastric adenocarcinoma and SPC-A-1, human lung adenocarcinoma) and inhibitory activities against Staphylococcus aureus ATCC 51650 were investigated.http://www.mdpi.com/1420-3049/17/11/13175&#947-butenolide derivativesspiculisporic acids B&#8211DAspergillus sp.marine fungus |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Xian-Ming Tang Quan-Ying Feng Ming-Qiu Yang Ming-Hui Shen Tian-Mi Liu Rong Wang Xiang-Min Li |
| spellingShingle |
Xian-Ming Tang Quan-Ying Feng Ming-Qiu Yang Ming-Hui Shen Tian-Mi Liu Rong Wang Xiang-Min Li Spiculisporic Acids B–D, Three New γ-Butenolide Derivatives from a Sea Urchin-Derived Fungus Aspergillus sp. HDf2 Molecules &#947 -butenolide derivatives spiculisporic acids B&#8211 D Aspergillus sp. marine fungus |
| author_facet |
Xian-Ming Tang Quan-Ying Feng Ming-Qiu Yang Ming-Hui Shen Tian-Mi Liu Rong Wang Xiang-Min Li |
| author_sort |
Xian-Ming Tang |
| title |
Spiculisporic Acids B–D, Three New γ-Butenolide Derivatives from a Sea Urchin-Derived Fungus Aspergillus sp. HDf2 |
| title_short |
Spiculisporic Acids B–D, Three New γ-Butenolide Derivatives from a Sea Urchin-Derived Fungus Aspergillus sp. HDf2 |
| title_full |
Spiculisporic Acids B–D, Three New γ-Butenolide Derivatives from a Sea Urchin-Derived Fungus Aspergillus sp. HDf2 |
| title_fullStr |
Spiculisporic Acids B–D, Three New γ-Butenolide Derivatives from a Sea Urchin-Derived Fungus Aspergillus sp. HDf2 |
| title_full_unstemmed |
Spiculisporic Acids B–D, Three New γ-Butenolide Derivatives from a Sea Urchin-Derived Fungus Aspergillus sp. HDf2 |
| title_sort |
spiculisporic acids b–d, three new γ-butenolide derivatives from a sea urchin-derived fungus aspergillus sp. hdf2 |
| publisher |
MDPI AG |
| series |
Molecules |
| issn |
1420-3049 |
| publishDate |
2012-11-01 |
| description |
Three new γ-butenolide derivatives 1–3, named spiculisporic acids B–D, were isolated from the culture of Aspergillus sp. HDf2, a marine-derived fungus that resides in the sea urchin, Anthocidaris crassispina. The structures of 1–3 were elucidated on the basis of spectroscopic methods, including MS and 2D NMR techniques. Their in vitro cytotoxic activities against two cell lines (SGC-7901, human gastric adenocarcinoma and SPC-A-1, human lung adenocarcinoma) and inhibitory activities against Staphylococcus aureus ATCC 51650 were investigated. |
| topic |
&#947 -butenolide derivatives spiculisporic acids B&#8211 D Aspergillus sp. marine fungus |
| url |
http://www.mdpi.com/1420-3049/17/11/13175 |
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