Nobiletin enhances the development and quality of bovine embryos in vitro during two key periods of embryonic genome activation

Abstract In vitro culture can alter the development and quality of bovine embryos. Therefore, we aimed to evaluate whether nobiletin supplementation during EGA improves embryonic development and blastocyst quality and if it affects PI3K/AKT signaling pathway. In vitro zygotes were cultured in SOF + ...

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Bibliographic Details
Main Authors: Karina Cañón-Beltrán, Yulia N. Cajas, Serafín Peréz-Cerezales, Claudia L. V. Leal, Ekaitz Agirregoitia, Alfonso Gutierrez-Adán, Encina M. González, Dimitrios Rizos
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-91158-7