HIV capsid is a tractable target for small molecule therapeutic intervention.

Despite a high current standard of care in antiretroviral therapy for HIV, multidrug-resistant strains continue to emerge, underscoring the need for additional novel mechanism inhibitors that will offer expanded therapeutic options in the clinic. We report a new class of small molecule antiretrovira...

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Bibliographic Details
Main Authors: Wade S Blair, Chris Pickford, Stephen L Irving, David G Brown, Marie Anderson, Richard Bazin, Joan Cao, Giuseppe Ciaramella, Jason Isaacson, Lynn Jackson, Rachael Hunt, Anne Kjerrstrom, James A Nieman, Amy K Patick, Manos Perros, Andrew D Scott, Kevin Whitby, Hua Wu, Scott L Butler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3000358?pdf=render