An iPSC-Derived Myeloid Lineage Model of Herpes Virus Latency and Reactivation

An iPSC-Derived Myeloid Lineage Model of Herpes Virus Latency and Reactivation

Herpesviruses undergo life-long latent infection which can be life-threatening in the immunocompromised. Models of latency and reactivation of human cytomegalovirus (HCMV) include primary myeloid cells, cells known to be important for HCMV latent carriage and reactivation in vivo. However, primary c...

Full description

Bibliographic Details
Main Authors: Emma Poole, Christopher J. Z. Huang, Jessica Forbester, Miri Shnayder, Aharon Nachshon, Baraa Kweider, Anna Basaj, Daniel Smith, Sarah Elizabeth Jackson, Bin Liu, Joy Shih, Fedir N. Kiskin, K. Roche, E. Murphy, Mark R. Wills, Nicholas W. Morrell, Gordon Dougan, Noam Stern-Ginossar, Amer A. Rana, John Sinclair
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Microbiology
Subjects:
human cytomegalovirus
latency
induced pluripotent stem cells
C2-iPSCs
viral carriage
myeloid
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.02233/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2019.02233/full

Similar Items