Biopharmacologic Properties of Resveratrol

• Main Authors: Syran Kakeh-Baraei, Elham Niroumand, Mozafar Khazaei
• Format: Article
• Language: fas
• Published: Vesnu Publications 2015-01-01
• Series: مجله دانشکده پزشکی اصفهان
• Subjects: Resveratrol; Antioxidant; Anticancer; Antidiabetic
• Online Access: http://jims.mui.ac.ir/index.php/jims/article/view/2917

Background: Resveratrol is a polyphenolic phytoalxine agent which is found in grapes, berries and peanuts. It is one of the important biomolecules with different biopharmacologic properties in modern medicine. To date, many experimental and animal researches were done on its properties and functions; the aim of present study was to introduce different properties of this important biomolecule. Methods: Acceptable database, Scopus, Pubmed and ISI, were searched with keyword of resveratrol. After the primary survey of the title by research team, and determination of common articles, abstracts of selected article were chosen and finally near to one hundred articles were included in the study. Important data were summarized and rewrite by research team, and were categorized and presented here. Findings: Resveratrol had antioxidant activities and was used in treatment of cardiovascular diseases, obesity and diabetes. In addition, it prevented gastric, lung, breast, and prostate, liver and colorectal cancer developments. Resveratrol showed anti-inflammatory, anti-aging and anti-Alzheimer's disease effects, and worked as regulator of cell cycle and programmed cell death (apoptosis). Resveratrol had strong estrogenic-like effects. Conclusion: Resveratrol is an important biomolecule with different medical properties which many studies were done on its new application and it get pivotal position in this area.