Nucleic acid amplification tests for diagnosis of smear-negative TB in a high HIV-prevalence setting: a prospective cohort study.

Nucleic acid amplification tests are sensitive for identifying Mycobacterium tuberculosis in populations with positive sputum smears for acid-fast bacilli, but less sensitive in sputum-smear-negative populations. Few studies have evaluated the clinical impact of these tests in low-income countries w...

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Bibliographic Details
Main Authors: J Lucian Davis, Laurence Huang, William Worodria, Henry Masur, Adithya Cattamanchi, Charles Huber, Cecily Miller, Patricia S Conville, Patrick Murray, Joseph A Kovacs
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3029312?pdf=render