Discovery and validation of a prostate cancer genomic classifier that predicts early metastasis following radical prostatectomy.

Discovery and validation of a prostate cancer genomic classifier that predicts early metastasis following radical prostatectomy.

Clinicopathologic features and biochemical recurrence are sensitive, but not specific, predictors of metastatic disease and lethal prostate cancer. We hypothesize that a genomic expression signature detected in the primary tumor represents true biological potential of aggressive disease and provides...

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Bibliographic Details
Main Authors: Nicholas Erho, Anamaria Crisan, Ismael A Vergara, Anirban P Mitra, Mercedeh Ghadessi, Christine Buerki, Eric J Bergstralh, Thomas Kollmeyer, Stephanie Fink, Zaid Haddad, Benedikt Zimmermann, Thomas Sierocinski, Karla V Ballman, Timothy J Triche, Peter C Black, R Jeffrey Karnes, George Klee, Elai Davicioni, Robert B Jenkins
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3691249?pdf=render

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http://europepmc.org/articles/PMC3691249?pdf=render

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