Influence of methadone on clopidogrel in addicts on methadone maintenance therapy
Background: Clopidogrel is a prodrug that converts in the liver to an active thiol metabolite, which irreversibly inhibits the platelet P2Y12 adenosine diphosphate receptor. It seems that methadone as CYP2C19 inhibitor affects ticlopidine activity in vivo. This study aimed to test the ability of met...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Babol University of Medical Sciences
2016-04-01
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| Series: | Caspian Journal of Internal Medicine |
| Subjects: | |
| Online Access: | http://caspjim.com/browse.php?a_code=A-10-256-1&slc_lang=en&sid=1 |