Characterization of the transcriptome profiles related to globin gene switching during <it>in vitro </it>erythroid maturation

Characterization of the transcriptome profiles related to globin gene switching during <it>in vitro </it>erythroid maturation

<p>Abstract</p> <p>Background</p> <p>The fetal and adult globin genes in the human β-globin cluster on chromosome 11 are sequentially expressed to achieve normal hemoglobin switching during human development. The pharmacological induction of fetal γ-globin (<it>HB...

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Bibliographic Details
Main Authors: Li Biaoru, Ding Lianghao, Li Wei, Story Michael D, Pace Betty S
Format: Article
Language:English
Published: BMC 2012-04-01
Series:BMC Genomics
Subjects:
Gene profiling
Erythroid maturation
γ-globin
β-globin
Hemoglobin switching
Fetal hemoglobin
Online Access:http://www.biomedcentral.com/1471-2164/13/153

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http://www.biomedcentral.com/1471-2164/13/153

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