Increased growth ability and pathogenicity of American- and Pacific-subtype Zika virus (ZIKV) strains compared with a Southeast Asian-subtype ZIKV strain.

Increased growth ability and pathogenicity of American- and Pacific-subtype Zika virus (ZIKV) strains compared with a Southeast Asian-subtype ZIKV strain.

We investigated the growth properties and virulence in mice of three Zika virus (ZIKV) strains of Asian/American lineage, PRVABC59, ZIKV/Hu/Chiba/S36/2016 (ChibaS36), and ZIKV/Hu/NIID123/2016 (NIID123), belonging to the three distinct subtypes of this lineage. The American-subtype strain, PRVABC59,...

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Bibliographic Details
Main Authors: Yasuhiro Kawai, Eri Nakayama, Kenta Takahashi, Satoshi Taniguchi, Ken-Ichi Shibasaki, Fumihiro Kato, Takahiro Maeki, Tadaki Suzuki, Shigeru Tajima, Masayuki Saijo, Chang-Kweng Lim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-06-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0007387

Internet

https://doi.org/10.1371/journal.pntd.0007387

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