Sialic acid-engineered mesoporous polydopamine dual loaded with ferritin gene and SPIO for achieving endogenous and exogenous synergistic T2-weighted magnetic resonance imaging of HCC

Sialic acid-engineered mesoporous polydopamine dual loaded with ferritin gene and SPIO for achieving endogenous and exogenous synergistic T2-weighted magnetic resonance imaging of HCC

Abstract Background Hepatocellular carcinoma (HCC) is a common malignant tumor with poor prognosis. Magnetic resonance imaging (MRI) is one of the most effective imaging methods for the early diagnosis of HCC. However, the current MR contrast agents are still facing challenges in the early diagnosis...

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Bibliographic Details
Main Authors: Kai Fan, Chengying Lu, Gaofeng Shu, Xiu-Ling Lv, Enqi Qiao, Nannan Zhang, Minjiang Chen, Jingjing Song, Fazong Wu, Zhongwei Zhao, Xiaoling Xu, Min Xu, Chunmiao Chen, Weibin Yang, Jihong Sun, Yongzhong Du, Jiansong Ji
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Journal of Nanobiotechnology
Subjects:
Magnetic resonance imaging
Superparamagnetic iron oxide
Polydopamine
Ferritin gene
Hepatocellular carcinoma
Online Access:https://doi.org/10.1186/s12951-021-00821-8

Internet

https://doi.org/10.1186/s12951-021-00821-8

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