An immune basis for malaria protection by the sickle cell trait.

An immune basis for malaria protection by the sickle cell trait.

<h4>Background</h4>Malaria resistance by the sickle cell trait (genotype HbAS) has served as the prime example of genetic selection for over half a century. Nevertheless, the mechanism of this resistance remains the subject of considerable debate. While it probably involves innate factor...

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Bibliographic Details
Main Authors: Thomas N Williams, Tabitha W Mwangi, David J Roberts, Neal D Alexander, David J Weatherall, Sammy Wambua, Moses Kortok, Robert W Snow, Kevin Marsh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2005-05-01
Series:PLoS Medicine
Online Access:https://doi.org/10.1371/journal.pmed.0020128

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https://doi.org/10.1371/journal.pmed.0020128

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