Self-Immolative nanoparticles for stimuli-triggered activation, covalent trapping and accumulation of in situ generated small molecule theranostic fragments
Small molecule theranostic agents suffer from fast blood clearance whereas nanoparticle ones are incapable of molecular functions and often nondegradable. We propose to bridge the gap between nanoparticles and small molecule agents based on self-immolative polymers which undergo triggered cascade de...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2020-03-01
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| Series: | Giant |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666542520300151 |