Analysis of SARS-CoV-2 vertical transmission during pregnancy

The impact of SARS-CoV-2 infection in pregnancy remains underexplored. Here, the authors provide a comprehensive characterization of virus and immunological parameters in 31 SARS-CoV-2-infected pregnant women, finding evidence of vertical transmission in two of the mother-child pairs.

Bibliographic Details
Main Authors:	Claudio Fenizia, Mara Biasin, Irene Cetin, Patrizia Vergani, Davide Mileto, Arsenio Spinillo, Maria Rita Gismondo, Francesca Perotti, Clelia Callegari, Alessandro Mancon, Selene Cammarata, Ilaria Beretta, Manuela Nebuloni, Daria Trabattoni, Mario Clerici, Valeria Savasi
Format:	Article
Language:	English
Published:	Nature Publishing Group 2020-10-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-020-18933-4

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spelling	doaj-88e732396d8a4d7084589eee41b6af922021-05-11T09:03:42ZengNature Publishing GroupNature Communications2041-17232020-10-0111111010.1038/s41467-020-18933-4Analysis of SARS-CoV-2 vertical transmission during pregnancyClaudio Fenizia0Mara Biasin1Irene Cetin2Patrizia Vergani3Davide Mileto4Arsenio Spinillo5Maria Rita Gismondo6Francesca Perotti7Clelia Callegari8Alessandro Mancon9Selene Cammarata10Ilaria Beretta11Manuela Nebuloni12Daria Trabattoni13Mario Clerici14Valeria Savasi15Department of Pathophysiology and Transplantation, University of MilanDepartment of Biomedical and Clinical Sciences, University of MilanDepartment of Woman, Mother and Neonate Buzzi Children’s Hospital, ASST Fatebenefratelli‐Sacco, Department of Biomedical and Clinical SciencesDepartment of Maternal Fetal Medicine, Fondazione MBBM, San Gerardo Hospital, University of Milan-BicoccaClinical Microbiology, Virology and Bio-emergence Diagnosis, ASST Fatebenefratelli-Sacco, Department of Biomedical and Clinical Sciences, University of MilanDepartment of Obstetrics and Gynecology, IRCCS Fondazione Policlinico San Matteo, University of PaviaClinical Microbiology, Virology and Bio-emergence Diagnosis, ASST Fatebenefratelli-Sacco, Department of Biomedical and Clinical Sciences, University of MilanDepartment of Obstetrics and Gynecology, IRCCS Fondazione Policlinico San MatteoDepartment of Maternal Fetal Medicine, Fondazione MBBM, San Gerardo Hospital, University of Milan-BicoccaClinical Microbiology, Virology and Bio-emergence Diagnosis, ASST Fatebenefratelli-Sacco, Department of Biomedical and Clinical Sciences, University of MilanUnit of Obstetrics and Gynecology, ASST Fatebenefratelli-Sacco, Department of Biological and Clinical Sciences, University of MilanDivision of Infectious Diseases, San Gerardo Hospital, ASST MonzaPathology Unit, ASST Fatebenfretalli-Sacco, Department of Biological and Clinical Sciences, University of MilanDepartment of Biomedical and Clinical Sciences, University of MilanDepartment of Pathophysiology and Transplantation, University of MilanUnit of Obstetrics and Gynecology, ASST Fatebenefratelli-Sacco, Department of Biological and Clinical Sciences, University of MilanThe impact of SARS-CoV-2 infection in pregnancy remains underexplored. Here, the authors provide a comprehensive characterization of virus and immunological parameters in 31 SARS-CoV-2-infected pregnant women, finding evidence of vertical transmission in two of the mother-child pairs.https://doi.org/10.1038/s41467-020-18933-4
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Claudio Fenizia Mara Biasin Irene Cetin Patrizia Vergani Davide Mileto Arsenio Spinillo Maria Rita Gismondo Francesca Perotti Clelia Callegari Alessandro Mancon Selene Cammarata Ilaria Beretta Manuela Nebuloni Daria Trabattoni Mario Clerici Valeria Savasi
spellingShingle	Claudio Fenizia Mara Biasin Irene Cetin Patrizia Vergani Davide Mileto Arsenio Spinillo Maria Rita Gismondo Francesca Perotti Clelia Callegari Alessandro Mancon Selene Cammarata Ilaria Beretta Manuela Nebuloni Daria Trabattoni Mario Clerici Valeria Savasi Analysis of SARS-CoV-2 vertical transmission during pregnancy Nature Communications
author_facet	Claudio Fenizia Mara Biasin Irene Cetin Patrizia Vergani Davide Mileto Arsenio Spinillo Maria Rita Gismondo Francesca Perotti Clelia Callegari Alessandro Mancon Selene Cammarata Ilaria Beretta Manuela Nebuloni Daria Trabattoni Mario Clerici Valeria Savasi
author_sort	Claudio Fenizia
title	Analysis of SARS-CoV-2 vertical transmission during pregnancy
title_short	Analysis of SARS-CoV-2 vertical transmission during pregnancy
title_full	Analysis of SARS-CoV-2 vertical transmission during pregnancy
title_fullStr	Analysis of SARS-CoV-2 vertical transmission during pregnancy
title_full_unstemmed	Analysis of SARS-CoV-2 vertical transmission during pregnancy
title_sort	analysis of sars-cov-2 vertical transmission during pregnancy
publisher	Nature Publishing Group
series	Nature Communications
issn	2041-1723
publishDate	2020-10-01
description	The impact of SARS-CoV-2 infection in pregnancy remains underexplored. Here, the authors provide a comprehensive characterization of virus and immunological parameters in 31 SARS-CoV-2-infected pregnant women, finding evidence of vertical transmission in two of the mother-child pairs.
url	https://doi.org/10.1038/s41467-020-18933-4
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Analysis of SARS-CoV-2 vertical transmission during pregnancy

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