Heme Oxygenase-1 Expression Affects Murine Abdominal Aortic Aneurysm Progression.

Heme Oxygenase-1 Expression Affects Murine Abdominal Aortic Aneurysm Progression.

Heme oxygenase-1 (HO-1), the rate-limiting enzyme in heme degradation, is a cytoprotective enzyme upregulated in the vasculature by increased flow and inflammatory stimuli. Human genetic data suggest that a diminished HO-1 expression may predispose one to abdominal aortic aneurysm (AAA) development....

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Bibliographic Details
Main Authors: Junya Azuma, Ronald J Wong, Takeshi Morisawa, Mark Hsu, Lars Maegdefessel, Hui Zhao, Flora Kalish, Yosuke Kayama, Matthew B Wallenstein, Alicia C Deng, Joshua M Spin, David K Stevenson, Ronald L Dalman, Philip S Tsao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4760983?pdf=render

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http://europepmc.org/articles/PMC4760983?pdf=render

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