Targeted next-generation sequencing at copy-number breakpoints for personalized analysis of rearranged ends in solid tumors.

Targeted next-generation sequencing at copy-number breakpoints for personalized analysis of rearranged ends in solid tumors.

BACKGROUND: The concept of the utilization of rearranged ends for development of personalized biomarkers has attracted much attention owing to its clinical applicability. Although targeted next-generation sequencing (NGS) for recurrent rearrangements has been successful in hematologic malignancies,...

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Main Authors: Hyun-Kyoung Kim, Won Cheol Park, Kwang Man Lee, Hai-Li Hwang, Seong-Yeol Park, Sungbin Sorn, Vishal Chandra, Kwang Gi Kim, Woong-Bae Yoon, Joon Seol Bae, Hyoung Doo Shin, Jong-Yeon Shin, Ju-Young Seoh, Jong-Il Kim, Kyeong-Man Hong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4061055?pdf=render

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http://europepmc.org/articles/PMC4061055?pdf=render

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