Liver accumulation of Plasmodium chabaudi-infected red blood cells and modulation of regulatory T cell and dendritic cell responses.

It is postulated that accumulation of malaria-infected Red Blood Cells (iRBCs) in the liver could be a parasitic escape mechanism against full destruction by the host immune system. Therefore, we evaluated the in vivo mechanism of this accumulation and its potential immunological consequences. A mas...

Full description

Bibliographic Details
Main Authors: Márcia M Medeiros, Henrique B da Silva, Aramys S Reis, Renato Barboza, Joanne Thompson, Maria Regina D'Império Lima, Cláudio R F Marinho, Carlos E Tadokoro
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3842419?pdf=render