Unambiguous detection of multiple TP53 gene mutations in AAN-associated urothelial cancer in Belgium using laser capture microdissection.

Unambiguous detection of multiple TP53 gene mutations in AAN-associated urothelial cancer in Belgium using laser capture microdissection.

In the Balkan and Taiwan, the relationship between exposure to aristolochic acid and risk of urothelial neoplasms was inferred from the A>T genetic hallmark in TP53 gene from malignant cells. This study aimed to characterize the TP53 mutational spectrum in urothelial cancers consecutive to Aristo...

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Bibliographic Details
Main Authors: Selda Aydin, Anne-France Dekairelle, Jérôme Ambroise, Jean-François Durant, Michel Heusterspreute, Yves Guiot, Jean-Pierre Cosyns, Jean-Luc Gala
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4153646?pdf=render

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http://europepmc.org/articles/PMC4153646?pdf=render

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