RNA sequencing identifies novel non-coding RNA and exon-specific effects associated with cigarette smoking

RNA sequencing identifies novel non-coding RNA and exon-specific effects associated with cigarette smoking

Abstract Background Cigarette smoking is the leading modifiable risk factor for disease and death worldwide. Previous studies quantifying gene-level expression have documented the effect of smoking on mRNA levels. Using RNA sequencing, it is possible to analyze the impact of smoking on complex regul...

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Bibliographic Details
Main Authors: Margaret M. Parker, Robert P. Chase, Andrew Lamb, Alejandro Reyes, Aabida Saferali, Jeong H. Yun, Blanca E. Himes, Edwin K. Silverman, Craig P. Hersh, Peter J. Castaldi
Format: Article
Language:English
Published: BMC 2017-10-01
Series:BMC Medical Genomics
Subjects:
RNA-seq
Differential expression
Cigarette smoking
Exon usage
Isoforms
Online Access:http://link.springer.com/article/10.1186/s12920-017-0295-9

Internet

http://link.springer.com/article/10.1186/s12920-017-0295-9

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