α-Trifluoromethyl Chalcones as Potent Anticancer Agents for Androgen Receptor-Independent Prostate Cancer

α-Trifluoromethyl chalcones were prepared and evaluated for their antiproliferative activities against androgen-independent prostate cancer cell lines as well as five additional types of human tumor cell lines. The most potent chalcone <b>5</b> showed superior antitumor activity in vivo...

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Bibliographic Details
Main Authors: Yohei Saito, Atsushi Mizokami, Kouji Izumi, Renato Naito, Masuo Goto, Kyoko Nakagawa-Goto
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/26/9/2812