A new candidate vaccine for human brucellosis based on influenza viral vectors: a preliminary investigation for the development of an immunization schedule in a guinea pig model

A new candidate vaccine for human brucellosis based on influenza viral vectors: a preliminary investigation for the development of an immunization schedule in a guinea pig model

Abstract Background A new candidate vector vaccine against human brucellosis based on recombinant influenza viral vectors (rIVV) subtypes H5N1 expressing Brucella outer membrane protein (Omp) 16, L7/L12, Omp19 or Cu–Zn SOD proteins has been developed. This paper presents the results of the study of...

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Bibliographic Details
Main Authors: Dina Bugybayeva, Zhailaubay Kydyrbayev, Nadezhda Zinina, Nurika Assanzhanova, Bolat Yespembetov, Yerken Kozhamkulov, Kunsulu Zakarya, Sholpan Ryskeldinova, Kaissar Tabynov
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Infectious Diseases of Poverty
Subjects:
Human brucellosis
Influenza viral vectors
Vaccine candidate
Protection
Guinea pigs
Immunization route
Online Access:https://doi.org/10.1186/s40249-021-00801-y

Internet

https://doi.org/10.1186/s40249-021-00801-y

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