The Epstein-Barr Virus BART miRNA Cluster of the M81 Strain Modulates Multiple Functions in Primary B Cells.

The Epstein-Barr virus (EBV) is a B lymphotropic virus that infects the majority of the human population. All EBV strains transform B lymphocytes, but some strains, such as M81, also induce spontaneous virus replication. EBV encodes 22 microRNAs (miRNAs) that form a cluster within the BART region of...

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Bibliographic Details
Main Authors: Xiaochen Lin, Ming-Han Tsai, Anatoliy Shumilov, Remy Poirey, Helmut Bannert, Jaap M Middeldorp, Regina Feederle, Henri-Jacques Delecluse
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-12-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1005344