Regulating cytoplasmic calcium homeostasis can reduce aluminum toxicity in yeast.

Our previous study suggested that increased cytoplasmic calcium (Ca) signals may mediate aluminum (Al) toxicity in yeast (Saccharomyces cerevisiae). In this report, we found that a yeast mutant, pmc1, lacking the vacuolar calcium ion (Ca(2+)) pump Ca(2+)-ATPase (Pmc1p), was more sensitive to Al trea...

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Bibliographic Details
Main Authors: Xuan Li, Jia Qian, Chaoqun Wang, Ke Zheng, Lan Ye, Yu Fu, Ning Han, Hongwu Bian, Jianwei Pan, Junhui Wang, Muyuan Zhu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3115986?pdf=render