Pharmacokinetics, optimal dosing, and safety of linezolid in children with multidrug-resistant tuberculosis: Combined data from two prospective observational studies.

<h4>Background</h4>Linezolid is increasingly important for multidrug-resistant tuberculosis (MDR-TB) treatment. However, among children with MDR-TB, there are no linezolid pharmacokinetic data, and its adverse effects have not yet been prospectively described. We characterised the pharma...

Full description

Bibliographic Details
Main Authors: Anthony J Garcia-Prats, H Simon Schaaf, Heather R Draper, Maria Garcia-Cremades, Jana Winckler, Lubbe Wiesner, Anneke C Hesseling, Rada M Savic
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-04-01
Series:PLoS Medicine
Online Access:https://doi.org/10.1371/journal.pmed.1002789