Hyperglycemia- Induced NF-κB Activation Increases microRNA-146a Expression in Human Umbilical Vein Endothelial Cells

Background & objectives: Nuclear Factor kappa B (NF-κB), a master switch transcription factor, plays a critical role in the progression and development of hyperglycemia-induced microangiopathy. Hyperglycemia activates NF-κB, and subsequently increases pro-inflammatory cytokines such as TNF-α, IL...

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Bibliographic Details
Main Authors: Elnaz Salmani Korjan, Kamila Kamali, Majid Katebi, Afshin Samiei, Farhad Ghadiri Soufi
Format: Article
Language:fas
Published: Ardabil University of Medical Sciences 2019-04-01
Series:Journal of Ardabil University of Medical Sciences
Subjects:
Online Access:http://jarums.arums.ac.ir/article-1-1649-en.html