Transition of tumor-associated macrophages from MHC class II<sup>hi </sup>to MHC class II<sup>low </sup>mediates tumor progression in mice
<p>Abstract</p> <p>Background</p> <p>Tumor-associated macrophages (TAMs) are the most abundant immune cells within the tumor stroma and play a crucial role in tumor development. Although clinical investigations indicate that high levels of macrophage (MΦ) infiltration i...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2011-08-01
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| Series: | BMC Immunology |
| Online Access: | http://www.biomedcentral.com/1471-2172/12/43 |