IL-4/IL-13 polarization of macrophages enhances Ebola virus glycoprotein-dependent infection.

<h4>Background</h4>Ebolavirus (EBOV) outbreaks, while sporadic, cause tremendous morbidity and mortality. No therapeutics or vaccines are currently licensed; however, a vaccine has shown promise in clinical trials. A critical step towards development of effective therapeutics is a better...

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Bibliographic Details
Main Authors: Kai J Rogers, Bethany Brunton, Laura Mallinger, Dana Bohan, Kristina M Sevcik, Jing Chen, Natalie Ruggio, Wendy Maury
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-12-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0007819