Sedimentation Velocity Analytical Ultracentrifugation of Oxidized Recombinant Full-Length Factor VIII

Sedimentation Velocity Analytical Ultracentrifugation of Oxidized Recombinant Full-Length Factor VIII

Anti-drug antibodies to coagulation factor VIII (fVIII), often termed inhibitors, present the greatest economical and treatment related obstacle in the management of hemophilia A. Although several genetic and environmental risk factors associated with inhibitor development have been identified, the...

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Bibliographic Details
Main Authors: Philip M. Zakas, John F. Healey, Ian W. Smith, David Lillicrap, Pete Lollar
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Immunology
Subjects:
hemophilia A
factor VIII
oxidation
immunogenicity
analytical ultracentrifugation
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00150/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.00150/full

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