Combinations of protein-chemical complex structures reveal new targets for established drugs.

Biological networks are powerful tools for predicting undocumented relationships between molecules. The underlying principle is that existing interactions between molecules can be used to predict new interactions. Here we use this principle to suggest new protein-chemical interactions via the networ...

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Bibliographic Details
Main Authors: Olga V Kalinina, Oliver Wichmann, Gordana Apic, Robert B Russell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-05-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC3088657?pdf=render

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