SNPsplit: Allele-specific splitting of alignments between genomes with known SNP genotypes [version 2; referees: 3 approved]

Sequencing reads overlapping polymorphic sites in diploid mammalian genomes may be assigned to one allele or the other. This holds the potential to detect gene expression, chromatin modifications, DNA methylation or nuclear interactions in an allele-specific fashion. SNPsplit is an allele-specific a...

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Bibliographic Details
Main Authors: Felix Krueger, Simon R. Andrews
Format: Article
Language:English
Published: F1000 Research Ltd 2016-07-01
Series:F1000Research
Subjects:
Online Access:http://f1000research.com/articles/5-1479/v2