Genetic associations with plasma B12, B6, and folate levels in an ischemic stroke population from the Vitamin Intervention for Stroke Prevention (VISP) trial

Genetic associations with plasma B12, B6, and folate levels in an ischemic stroke population from the Vitamin Intervention for Stroke Prevention (VISP) trial

B vitamins play an important role in homocysteine metabolism, with vitamin deficiencies resulting in increased levels of homocysteine and increased risk for stroke. We performed a genome-wide association study (GWAS) in 2,100 stroke patients from the Vitamin Intervention for Stroke Prevention (VISP)...

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Bibliographic Details
Main Authors: Keith L Keene, Wei-Min eChen, Fang eChen, Stephen Richardson Williams, Stacey D Elkhatib, Fang-Chi eHsu, Josyf C Mychaleckyj, Kimberley F Doheny, Elizabeth W Pugh, Hua eLing, Cathy C Laurie, Stephanie M Gogarten, Ebony B Madden, Bradford B Worrall, Michele M Sale
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-08-01
Series:Frontiers in Public Health
Subjects:
GWAS
Association
Folate
B12
VISP
one carbon metabolism
Online Access:http://journal.frontiersin.org/Journal/10.3389/fpubh.2014.00112/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fpubh.2014.00112/full

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