Pre-ischemic Lactate Levels Affect Post-ischemic Recovery in an Isolated Rat Heart Model of Donation After Circulatory Death (DCD)

Pre-ischemic Lactate Levels Affect Post-ischemic Recovery in an Isolated Rat Heart Model of Donation After Circulatory Death (DCD)

Introduction: Donation after circulatory death (DCD) could substantially improve donor heart availability. In DCD, the heart is not only exposed to a period of warm ischemia, but also to a damaging pre-ischemic phase. We hypothesized that the DCD-relevant pre-ischemic lactate levels negatively affec...

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Bibliographic Details
Main Authors: Maria Arnold, Adrian Segiser, Selianne Graf, Natalia Méndez-Carmona, Maria N. Sanz, Rahel K. Wyss, Nina Kalbermatter, Nino Keller, Thierry Carrel, Sarah Longnus
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
cardiac ischemia reperfusion injury
donation after circulatory death
heart transplantation
lactate
contractile function
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2021.669205/full

Internet

https://www.frontiersin.org/articles/10.3389/fcvm.2021.669205/full

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