WSZG inhibits BMSC-induced EMT and bone metastasis in breast cancer by regulating TGF-β1/Smads signaling

WSZG inhibits BMSC-induced EMT and bone metastasis in breast cancer by regulating TGF-β1/Smads signaling

Bone metastasis of breast cancer causes severe skeletal-related events and poor prognosis. Wensheng Zhuanggu Formula (WSZG), a traditional Chinese prescription, is used to adjunctively treat breast cancer bone metastases in clinical practice. This study was undertaken to investigate the antibone-met...

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Bibliographic Details
Main Authors: Jiao Ma, Jiajia Li, Ying Wang, Weiling Chen, Peiyong Zheng, Yueqiang Chen, Zhenping Sun, Jin Liu, Yin Zhou, Jianyi Wang, Sheng Liu, Xianghui Han
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Breast cancer
Bone
Metastasis
Wenshen Zhuanggu Formula
Bone marrow-derived mesenchymal stem cell
Epithelial-mesenchymal transition
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332219352394

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http://www.sciencedirect.com/science/article/pii/S0753332219352394

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