Losses of cytokines and chemokines are common genetic features of human cancers: the somatic copy number alterations are correlated with patient prognoses and therapeutic resistance

Losses of cytokines and chemokines are common genetic features of human cancers: the somatic copy number alterations are correlated with patient prognoses and therapeutic resistance

Intricate relationships among cytokines (including chemokines) shape the tumor microenvironment (TME) and reflect cell-cell interactions between malignant cells and other cells from the TME. Although our previous study indicated the transcriptional landscape of cytokines in 19 cancer types, the glob...

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Bibliographic Details
Main Authors: Henry Sung-Ching Wong, Wei-Chiao Chang
Format: Article
Language:English
Published: Taylor & Francis Group 2018-09-01
Series:OncoImmunology
Subjects:
somatic copy number (scn) alterations
cancer genetic landscape
cytokines
chemokines
pan-cancer bioinformatics analysis
Online Access:http://dx.doi.org/10.1080/2162402X.2018.1468951

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