Treatment of severe hospital-acquired and ventilator-associated pneumonia: a systematic review of inclusion and judgment criteria used in randomized controlled trials

Treatment of severe hospital-acquired and ventilator-associated pneumonia: a systematic review of inclusion and judgment criteria used in randomized controlled trials

Abstract Background Hospital-acquired and ventilator-associated pneumonia (HAP/VAP) are often selected for randomized clinical trials (RCTs) aiming at new drug approval. Guidelines for the design of such RCTs have been repeatedly updated by regulatory agencies. We hypothesized that large variability...

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Bibliographic Details
Main Authors: Emmanuel Weiss, Wafa Essaied, Christophe Adrie, Jean-Ralph Zahar, Jean-François Timsit
Format: Article
Language:English
Published: BMC 2017-06-01
Series:Critical Care
Subjects:
Systematic review
Hospital-acquired pneumonia treatment
Ventilator-acquired pneumonia treatment
Randomized controlled trials
Endpoints
Inclusion criteria
Online Access:http://link.springer.com/article/10.1186/s13054-017-1755-5

Internet

http://link.springer.com/article/10.1186/s13054-017-1755-5

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