The Putative Roles and Functions of Indel, Repetition and Duplication Events in Alphavirus Non-Structural Protein 3 Hypervariable Domain (nsP3 HVD) in Evolution, Viability and Re-Emergence

The Putative Roles and Functions of Indel, Repetition and Duplication Events in Alphavirus Non-Structural Protein 3 Hypervariable Domain (nsP3 HVD) in Evolution, Viability and Re-Emergence

Alphavirus non-structural proteins 1–4 (nsP1, nsP2, nsP3, and nsP4) are known to be crucial for alphavirus RNA replication and translation.<b> </b>To date, nsP3 has been demonstrated to mediate many virus–host protein–protein interactions in several fundamental alphavirus mechanisms, par...

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Bibliographic Details
Main Authors: Nurshariza Abdullah, Nafees Ahemad, Konstantinos Aliazis, Jasmine Elanie Khairat, Thong Chuan Lee, Siti Aisyah Abdul Ahmad, Nur Amelia Azreen Adnan, Nur Omar Macha, Sharifah Syed Hassan
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Viruses
Subjects:
alphavirus
nsP3
HVD
indel
repetition
duplication
Online Access:https://www.mdpi.com/1999-4915/13/6/1021

Internet

https://www.mdpi.com/1999-4915/13/6/1021

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