Co-Delivery of Imiquimod and Plasmid DNA via an Amphiphilic pH-Responsive Star Polymer that Forms Unimolecular Micelles in Water

Dual functional unimolecular micelles based on a pH-responsive amphiphilic star polymer β-CD-(PLA-b-PDMAEMA-b-PEtOxMA)21 have been developed for the co-delivery of imiquimod and plasmid DNA to dendritic cells. The star polymer with well-defined triblock arms was synthesized by combining activator re...

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Bibliographic Details
Main Authors: Wenjing Lin, Na Yao, Hongru Li, Samuel Hanson, Wenqing Han, Chun Wang, Lijuan Zhang
Format: Article
Language:English
Published: MDPI AG 2016-11-01
Series:Polymers
Subjects:
Online Access:http://www.mdpi.com/2073-4360/8/11/397